Neuroblastoma (NB), a devastating pediatric cancer originating from neural crest cells crucial for nervous system development, poses a significant therapeutic challenge.Despite chemotherapy being the primary treatment, approximately 70% of high-risk NB cases develop resistance.Autophagy is vital for neuronal development, balance, and differentiatio
Influence of a lifestyle intervention in preschool children on physiological and psychological parameters (Ballabeina): study design of a cluster randomized controlled trial
Abstract Background Childhood obesity and physical inactivity are increasing dramatically worldwide.Children of low socioeconomic status and/or children of migrant background are especially at risk.In general, the overall effectiveness of school-based programs on health-related outcomes has been disappointing.A special gap exists for younger childr
Geological Composition and Structure of the Filling Zone and Its Water-Resisting Property Evaluation on the Top of Ordovician Limestone
With the gradual increase in mining depth of coal fields in North China, the threat posed by karstic Ordovician limestone water to the safe stoping of mines is becoming increasingly prominent.Investigating the water-resisting property of the filling zone on the top of the Ordovician limestone provides the key to safe mining under pressure.This pape
THE PAIN AND THE TEAR IN CINEMA AND LITERATURE: A PRELIMINARY STUDY
This article is based in the literary works and filmic Anna Karnina, The Lady of the Camellias and Lucola, in which we want to establish the relationship between the respective protagonists who have similar feelings about love, suffering empire bump hair and tears, and, during their life trajectories their destinations culminate to the same purpose